Journal of Hard Tissue Biology
Online ISSN : 1880-828X
Print ISSN : 1341-7649
ISSN-L : 1341-7649
Original
Expression of Chromogranin A in the Mouse Dental Pulp and Periodontal Tissues
Masahiro Sato, Keisuke Nakano, Shinnosuke Saito, Atsushi Nabeyama, Norimasa Okafuji, Akio Yamamoto, Etsuo Kasahara, Hiromasa Hasegawa, Toshiyuki Kawakami
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Keywords: Chromogranin A, Mechanical stress, Immediate teeth separation, Operative dentistry, Dental pulp, Periodontal tissue, Immunohistochemistry
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2011 Volume 20 Issue 4 Pages 295-300

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Abstract
We examined immunohistochemical expression of Chromogranin A (CgA) in the mouse dental pulp and the periodontal tissues, which exposed to 3 hours immediate teeth separation. In the experimental group, CgA positive staining products were frequently detected in the periodontal fibroblasts and endothelial cells, and also detected in the dental pulp cells. The positive reactions were stronger than that of control specimens. The data suggests that induced expression was due to the mechanical stress of wedge insertion.
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© 2011 by The Hard Tissue Biology Network Association(JHTBNet)
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