化学療法/放射線治療 −有害事象の評価と対策−

抄録

Recently, the standard treatment for head and neck cancer in each stage include various treatment modalities (surgery, radiotherapy and chemotherapy). Complex regimens such as TPF induction chemotherapy followed by cetuximab with radiotherapy or surgery followed by chemoradiotherapy have various adverse reactions and these often cause treatment interruption and multidisciplinary approaches are necessary. It is important that we have common recognition for the same matter in multidisciplinary treatment, however, I think we don't have enough skill to use common terminology criteria yet. As for hematological toxicities, there are objective borders between grade 1,2 and 3,4. On the other hand, most of non-hematological toxicities have subjective borders and this judgement often need global assessment which consist of findings, ADL and patient reported outcome (PRO). To evaluate non-hematological toxicities, discussions with medical staffs are mandatory. Then, we should discuss about how to use 'terminology' in clinical practice.