抄録
Lysozyme chloride, which was extracted from egg white was used for 20 cases of vertigo and dizziness including Ménière's disease. This therapeutic enzyme on mucous membrane was administered by mouth in daily doses of from 30mg to 60mg.
Curative effects on the attack of vertigo were observed in 13 cases(65%), while there were no improvement of cochlear dysfunction except 3 cases of tinnitus. As a side-effect, nausea appeared only 1 case developed in a 28 year old male sufferring from cervical syndrom.
By our investigations it is thought that enzyme took part in metabolic process of the inner ear, therefore it is a drug to be applied for aural vertigo generally. Though little discussion has been carried on the detailed functional mechanism or a number of clinical experiences.
