Abstract
The author recently experienced a case of penicillin-anaphylaxis in treating chronic sinusitis. After a female patient, aged 23, had penicillin poured into the maxillary sinus and sprayed into the nasal cavity, she showed penicillin-anaphylaxis. The clinical progress and the bibliographical study of this case are reported.
The author considered that this case belonged to Weiss's contact dermatitis and the hypersensitivity had been acquired by penicillininjection in the operation of appendicitis performd in January this year. He considered also that, as Goltman said, the patient had been made sensitive by inhalation of filamentous fungi, because she was a worker at a bakery shop, and her constitutional defect also contributed to this hypersensitivity.
For preventive measures, patients should to asked if they have Lad penicillin in the past and given the examination of Mayer's intracuticular reaction. But to clinicians, spray of a small amount of penicillin into the nasel cavity is convenient and no less reliable than the general allergic examination. The author stresses that clinicians should endeavor to prevent penicillin-anaphylaxis which tends to increase.
