耳鼻と臨床
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
緑膿菌性中耳炎の免疫血清学的研究
OEP-HA 反応を中心にして
都川 紀正
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ジャーナル フリー

1981 年 27 巻 1Supplement1 号 p. 189-194

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Pseudomonas infection has been increasing in number these days and pseudomonal otitis media have been found in the otolaryngological practice. Pseudomonal infections are caused by bacterial substitution phenomena, burns, tissue transplantations, major surgeries, endoscopic procedures, intensive radiation therapies and steroid therapy. We have great number of problems to treat this infection.
The author applied hemagglutination (OEP-HA reaction) to 33 patients of pseudomonal chronic otitis media and obtained the results on specific antibody to this bacillus. OEP (=Original Endotoxic Protein) is protective antigen located in cell wall of pseudomonas aeruginosa and is found in the group specific in its protective antigenicity. Antibody titer in normal human sera is under 1: 80. The specific antibody titer in 65 strains (33 patients) was ranged from under 1: 40 to over 1: 2560. The rate of 17 positive strains (over 1: 160) was 26.2 %. The antibody titer of most control strains was within normal limit.
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