The effect of specific immunotherapy was evaluated in 244 patients with nasal allergy whose treatment commenced more than 3 years ago. A course of therapy consisted of a large initial dose with maintenance dose injections for 3-6 months. 1. The success rate was 67.5% in the patients who completed one or more courses of treatment. If those who were recieving the maintenance dose were included, the success rate was 70.6%. 2. Among patients who discontinued treatment, those who were treated less than two years tended to have a recurrence of symptoms. 3. The cases suffering from nasal obstruction showed ineffective results. 4. Between pre-and post-immunotherapy, there was no significant difference in the examination results i. e. direct intradermal reaction, intranasal provocation test, eosinophile leucocyte count test of nasal smear and serum specific lgE antibody level.