抄録
Registered 404 autopsy cases of malignant tumors in the hypopharynx were collected from the Annual Records of the Pathological Autopsy Cases in Japan (1977 to 1984). These cases represented 0.2% of all malignant tumors. The sex ratio was 2.86. The median age was in the 70's in both sexes. The autopsy cases per 100,000 population of male and both sexes were higher in the Kanto and Kyushu districts than other districts. Histomorphologically 385 cases (95.3%) were squamous cell carcinomas, while 2 cases (0.5%) were adenocarcinomas, and 3 cases (0.7%) belonged to sarcomas (the remaining 14 cases (3.5%) were unknown). Metastasis into the lymph nodes was 47.7% in the carcinoma cases. The most frequent site of metastasis was the cervical lymph node, and the pneumonal-hilus-, mediastinal-, paraaortic lymph nodes followed in frequency. Distant metastasis was observed in 57.7% of cases. This incidence is higher than the clinical observation. Organs to which the tumor metastasized frequently were lung, bone, and liver.
