抄録
In cases of infectious disease, it is generally necessary to identify the bacterial pathogens involved, their susceptibility to antibitotics, and to determine the appropriate antimicrobial therapy. It is important to perform bacterial monitoring and appropriate chemotherapy, parallel with antimicrobial therapy. However, as for inflammatory diseases that are frequently encountered in routine clinical practice, such as acute otitis media and chronic sinusitis, it is difficult to perform bacterial examinations because the diseases occur in cavitates obturatum such as the middle ear cleft, paranasal sinus. By contrast, bacterial examination is easily performed for diseases of the nasopharynx, which lies close to the ear and nose and is recognized to be a site which is closely related to such inflammatory diseases. We studied nasopharyngeal microbiologic flora between healthy children and children with acute otitis media or chronic sinusitis at exacerbation, and time-course changes in bacterial flora of the nasopharynx in a case of acute otitis media. In result, the bacteriologic findings of the nasopharynx clearly reflected the clinical findings of the children with acute otitis media and chronic sinusitis at exacerbation.
