Abstract
The clinical efficacy of erythromycin treatment for chronic paranasal sinusitis in children (under 12 years of age) was retrospectively investigated. Sixty-four patients with chronic paranasal sinusitis were treated and followed. The efficacy of treatment was determined based on the intranasal findings and nasal X-rays. The intranasal findings after treatment for 3 to 4 months improved in 55%, while the nasal X-rays showed an improvement in 45%. We statistically studied the relationship between these results and the difference in age, sex, site degree of clouding in the nasal X rays, nasal allergy complications and the duration of the disease before beginning this treatment. The shorter the duration before initiating this treatment, the higher the response rate (P=0.045) for the nasal X-rays. In addition, the patients without nasal allergy had a statistically higher response rate in the nasal X-rays than those with nasal allergy (P=0.046). No relationship was found, however, in the other cases.
