耳鼻と臨床
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
外耳道湿疹より分離せるCandidaについて (補遺) Otomycosisの病因論に対する知見
古内 一郎
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ジャーナル フリー

1960 年 6 巻 2 号 p. 82-91

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The author reported here ten cases of the Candida detected from eczema of the external auditory meatus while he was engaging in the search for Candida from the secretion of the tympanum in 161 ears of chronic perforated otitis media.
Clinical findings showed that myringitis was combined in all cases, and in 5 of t hem there was otorrhea with a singular apperance scattering white corpuscles over the surface.
Among the separated Candida, C. albicans numbered six strains and predominated. In the immunoserological reaction of patients of Candida, the complement fixation reaction was negative and the agglutination reaction was positive below 160 times.
In bacilli detected, the 5 strains of Gram's negative stain were separated, and showed tolerance to CM used in the treatment.
The author pursued the relation of Candida with other bacilli using stored strains of proteus, pseudomonas and staphylococcus in his experiments, and found that proteus and pseudomonas having a tolerance to 10γ/cc CM had symbiosis with the Candida.
His cological study of the Candida separated, immunoserological findings of the patients from whom the Candida was separated and the experimental study combined to conclude that in eczema of the external auditory meatus from which the Candia was separated, primary infectious agents were Gram's negative bacilli, and the Candida was mixed bacilli, confirming the theory of Conley.
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