口蓋扁桃の上皮下基底膜に関する病理組織学的研究

抄録

In 129 palatine tonsils obtained from 121 cases in operation and autopsy, physiological and pathological changes in the free surface and subepithelial basement membrane of the lacuna were examined histopathologically and histochemically, and the following results were obtained.
1. The free surface and subepthelial basement membrane of the lacuna of the palatine tonsil were comprised of argyrophil fibers and ground substance, and secondary hyaline layer was observed in no cases. The same was found in ciliated epithelium which was seen sometimes in the lacuna.
2. In the subepithelial basement membrane was remarkably seen physiological loosening, which corresponded with the changes in inflammation stadium of the free surface. This was closely related to reticulation in the epithelial layer, state of follicles and the amount of fibers in parenchyma.
3. The loosening in the basment membrane was remarkable in infants and children lator, nearly in parallel to the involution of the tonsils, the membrane became compact in structure.
4. In inflammation, the basement membrane showed remarkable changes ranging from hatch formation to partial disappearance. In many cases, these changes were seen in areas which were not directly subjected to inflammatory stimulation.
5. The physiological loosening in the basement membrane was assumed to have been secondarily produced by the passage of lymphocytes, lymph and tissue fluid. It is considered that these changes would facilitate protective action on one hand, and contact of lacunar antigen and tonsil parenchyma on the other, which would contribute to the formation of antibody.