内耳液及び髄液のフラビン及びカタラーゼの消長に関する実験的研究

第1編 内耳液及び髄液のフラビンの消長に関する実験的研究 第2編 内耳液及び髄液のカタラーゼの消長に関する実験的研究

抄録

Part 1. Changes of Flavin in labyrinthine and cerebrospinal fluid in normal animal and those with experimental injury to the auditory orgarn.
Flavin was not found in labyrinthine and cerebrospinal fluid of normal rabbit, those in aller-gic states due to B.C.G. vaccine and those with injury to the auditory organ by sound. But, flavin was demonstrated in both fluid after the injection of flavin into the subarachnoid space. These results give the ground for the advocate that T. B. allergy is a cause of the so-called "perceptive deafness".
And the changes of flavin in the both fluid prove that the obstruction for the alternating process between labyrinthine and the spinal fluids was decreased.
Part. 2. Changes of Catalase in labyrinthine and cerebrospinal fluid in normal animal and those with exprimental injury to the auditory organ.
Catalase was always absent in labyrinthine and the cerebrospinal fluid of normal rabbits and those Vitamin B1 or Vitamin B2, injection was given. In rabbits in allergic state due to B.C.G. vaccine, catalase appeared in the both fluid, while in those animals Vitamin Bt or Vitamin B2 was injected catalase was decreased. From the resluts of these experiments, injection of Vitamin B1 or Vitamin B2 as therapeutic and preventive means for the labyrinthine disorder was effective.