糖尿病の中耳炎に及ぼす影響についての実験的研究

抄録

Two groups of rabbits, one with diabetes mellitus deneloped by alloxan injection, and another healthy groups for the contrast were studied. In each group, middle ear infection was developed by staphylococcus aureus injection in tympanic bulla.
The specimens of auditory organs were fixed in Wittmaack's solution, then embedded in celloidin and stained with hematoxylin-eosin.
The results of the examination were as follows:
In diabetes mellitus group, histopathological changes were more remarkable than that in contrast group on following points.
1) External auditory canal: Desquamation of the epithelium, celluler infilltration in subcutaneus tissue.
2) Tympanic cavity: Edema, celluler infiltration and bleeding in mucous membrane.
3) Bone absortion and Multiplication of tympanic cavity and tympanic bulla.
4) Periostal thickening, bone absorption in auditory ossicles.
5) Changes in inner ear were more remarkable and healing of inflammation was slower in diabetes mellitus group then in contrast group.