扁桃の免疫機能に関するウイルス学的研究

第1編 イソフルエンザと扁桃

抄録

In order to investigate the defence mechanism of infection of viruses in tonsils, theantibody value for influenza virus in tonsils and serum were measured and the following results were ob- tained. (Method) The hemagglutination inhibition test of Hirst was used in this experiment.
Samples were obtained from the extracts of palatine tonsil and serum of 147 patients who had tonsillectomies. As an antigen virus A1/Omachi /1/53.A2/Adachi/2/57, and B/Setagaya/3/56 were used. 1) Nonspecific hemaggltination inhibitor was found more frequently in the tonsils than in the serum.;in cases where it was found inboth, hi- gher titer in thetonsils was found.
2) Most of antibody values for A2 type in the tonsils were higher than the one in serum.
3) Instudying the newer epidemics of influ- enza, ahigher value of antihody for the same type of virus was found in the tonsils.The antibody in tonsilis gradually released into the serum with time.
4) ln comparing the group under 15 years old with one over 16 years old, the former showed higher values of hemagglutination inhibitor and higher percentage of antibody for every type of infinenza.
In conclusion, thetonsils seemed to besigni- ficant in producing antibody for virus and especia- lly in young subjects they are considered to have an important defence function against influenza infection.