耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
臨床
喉頭原発悪性リンパ腫例
石田 芳也林 達哉金井 直樹小林 祐希朝日 淳仁和田 哲治原渕 保明
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ジャーナル 認証あり

2009 年 102 巻 8 号 p. 651-657

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Malignant lymphoma of the larynx is very rare with a reported incidence of less than 1% of all laryngeal malignancies. A case of laryngeal non-Hodgkin's lymphoma (diffuse large B cell type) in an 89-year-old female is reported.
At the initial consultation, the patient had complained of abnormal sensation in the pharyngolaryngeal region that had persisted for a few days. Endoscopic examination demonstrated a supraglottic mass with a smooth surface. The histopathological diagnosis was diffuse large B cell lymphoma. There was no other evidence of lymphoma anywhere except a regional lymph node. The patient was diagnosed as having clinical stage IIEA and treated with 30 Gy's irradiation alone because of her poor performance status. Six months after the initial treatment, tumor recurrence occurred in the right tonsil and treated with chemoradiotherapy that was 3 courses of CHOP and 30 Gy's concurrent radiotherapy followed by 4 courses of R-CHOP. There was no recurrence observed for 8 months after completion of the last therapy.
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© 2009 耳鼻咽喉科臨床学会
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