口蓋扁桃摘出術が有効であったPFAPA症候群の2例

抄録

PFAPA syndrome is characterized by five features: Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis, occurring in children under 5 years of age. Periodic fever, the main symptom, persists for about 3–6 days, accompanied by aphthous stomatitis, pharyngitis, neck lymphadenitis. We reviewed the data of two patients with PFAPA syndrome treated by tonsillectomy. In one patient, no improvement of the symptonms was obtained in response to treatment with a steroid and H2 blocker prescribed by a pediatrician, and tonsillectomy was performed; the patient has had no symptoms since this treatment.

The other patient wished to undergo tonsillectomy even before being initiated on any medications such as a steroid or H2 blocker. Both the patients who underwent tonsillectomy have shown a good course since the tonsillectomy.

We believe the tonsillectomy is feasible and effective in patients with the PFAPA syndrome.