Children with adenoid symptoms reveal high levels of serum immunoglobulin D.
Several cases such were always accompanied by recurrent rhinosinusitis, relapsing otitis media and cervical lymphatic swelling.
We selected two such cases and described their clinical picture and course, and further demonstrated that the value of serum immunoglobulin D was remarkably decreased postoperatively by adenoidectomy.
There was a quasi-coincidence of time between the decrease of value of immunoglobulin D and the mechanism of healing of various complicated factors in these two cases. Furthermore, the serum immunoglobulin D remained low unless there was a relapse of the adenoid-symptoms or recurrent infections.
From these observations it is suggested that there is a close relation between the recurrent or relapsing infection (upper respiratory tract), adenoid tissue (Waldyer's ring) and serum immunoglobulin D.
