耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
抗ヒスタミン剤 Mequitazine (LM209) の鼻アレルギーに対する治療効果
玉田 彰加納 直行大川 正直野々村 光栄由井 正剛牧本 一男
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1983 年 76 巻 5 号 p. 1499-1504

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LM 209 is a new product of antihistamine to treat allergic diseases. We investi-gated the antiallergic activity of LM 209 for allergic rhinitis, using 24 patients appeared in the ENT clinic of Kyoto University Hospital and Nagahama Red Cross Hospital from Spring to July, 1982. This drug was given to each patient for 3 weeks continuously. The results obtained were as follows.
1) The effectiveness for sneezing, watery rhinorrhea and nasal obstruction was 79.2, 66.7 and 33.3% respectively.
2) Overall effectiveness for allergic rhinitis was 66.7%, including seasonal and perennial types.
3) The side effect of drowsiness and tiredness was minimal, for which a long term administration was feasible.
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