耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
咽頭炎および扁桃炎に対する「MK212G」の臨床評価
―イソジンガーグル®との二重盲検試験―
原田 康夫夜陣 紘治平川 勝洋中田 将風竹林 脩文築家 大介黒川 道徳村上 譲菊屋 義則野田 益弘二宮 優子笹 征史
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1986 年 79 巻 1 号 p. 161-172

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Patients with pharyngitis and tonsillitis were studied in a randomized double-blind trial to compare the clinical usefulness of MK212G and Isodine gargle.
1. Of the 71 patients treated with MK212G or Isodine gargle, four were excluded because they were out of protocol. The results in the remaining 32 patients treated with MK212G and 35 patients treated with Isodine gargle were analyzed statistically.
2. MK212G was effective in 93.8% and Isodine gargle in 85.7%, not a statistically significant difference (x2=3.807 N.S.).
3. In the MK212G group, one patient complained of oral discomfort and in the Isodine gargle group, two patients had mild nausea and one had vomitting. The difference was not statistically significant (x2=1.165 N. S.).
4. MK212G was considered to be clinically useful in 87.51% and Isodine gargle in 82.86%, not a statistically significant difference (x2=0.410 N. S.).
5. The above results suggest that MK212G is as useful as Isodine gargle in the treatment of pharyngitis and tonsillitis.
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