An 81-year-old male complaining of nasal obstraction, epistaxis, and zygomatic swelling was admitted to Osaka Medical College Hospital. The histological diagnosis was metastatic maxillary tumor from a primary hepatocellular carcinoma. We employed intra-arterial infusion of ADM and BLM. These drugs were delivered through Tefron® catheters which were inserted into the right superficial temporal artery and hepatic artery. However, his general condition deteriorated gradually, and he died of hepatic failure. At autopsy, hepatocellular carcinoma was found to be of the massive type and Edmondson's type II and to coexist with Nagayo's type A cirrhosis. It had metastasized to the right maxillary sinus, lungs, and right adrenal gland. These metastases were considered to be hematogenous.
