耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
83 巻, 5 号
選択された号の論文の23件中1~23を表示しています
  • 川端 五十鈴
    1990 年 83 巻 5 号 p. 685-692
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The clinical features and etiology of chronic granular myringitis were studied in our laboratory.
    Since Mofet reported the first cases of chronic granular myringitis in 1953, several authors have described the clinical features of this disease. According to them, it is characterized by local granulation of the tympanic membrane with otorrhea as the only symptom.
    Tuiki et al presented the following clinical definition of this disease:
    1. the only symptom is otorrhea
    2. there is little or no hearing loss
    3. x-rays of the mastoid show a well-developed air cell system
    4. non-specific bacteria are found in culture
    The cause of this disease is not known, but there might be two factors, exogenous and endogenous. The exogenous factor seems to be high temperature and high humidity leading to external ear canal infection. The endogenous factor might be an abnormality of the tympanic membrane.
    Scanning electron microscopic observations of the crust on the surface of the tympanic membrane now being done in our laboratory demonstrate bacterial colonies, crystal structures and epithelial cells on the surface of the crust. These findings suggest that bacterial colonies on the dry crust are a cause of reinfection in this disease. The crystal formation may be related to epithelial cells. The results are briefly discussed in relation to the etiology of this disease.
  • 滝元 徹, 吉崎 智一, 土定 建夫, 梅田 良三
    1990 年 83 巻 5 号 p. 694-695
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
  • ―ポジトロンCTによる研究―
    伊藤 壽一, 榊原 淳二, 本庄 巖, 岩崎 康, 米倉 義晴
    1990 年 83 巻 5 号 p. 697-700
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The speech comprehension ability of cochlear implant patients is fairly good in spite of the fact that insufficient information is being received from the cochlear implant device. It is presumed that the higher central nervous system has an important role in discriminating speech. The purpose of the present study was to investigate the function of the primary and associate auditory cortex of a cochlear implant patient before and after sound signal inputs from the cochlear implant device. In this study we used positron emission computed tomography (PET), which can detect brain activity by providing quantitative measurements of the regional cerebral blood flow and the metabolic rates of oxygen and glucose. Without sound signals the primary auditory cortex and associate cortex of cochlear the implant patient showed remarkably low metabolic rates. However, when the cochlear implant device was used, the activities of both cortices returned to near normal levels. These findings suggest that activation of the speech comprehension mechanism of the higher central nervous system can be initiated by simple sound signals from the cochlear implant device.
  • 平出 文久, 栫 博幸, 石田 孝
    1990 年 83 巻 5 号 p. 701-707
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The authors have examined 15 patients with sudden deafness and further progression of hearing loss after the initial examination. Eleven of the 15 patients (group A) showed the greatest degree of hearing loss during the first 8 days after the onset of deafness. The remaining 4 patients (group B) had the poorest hearing 1 month to 4 years after the sudden onset of hearing loss.
    Sudden hearing loss mainly of high frequencies suggests that the sensory disturbance starts in the basal turn and then progresses towards the apical turn of the cochlea. Hearing improved considerably in the patients of group A, but not at all in those of group B. There may be a definite difference in the pathogenesis of deafness between group A and group B.
  • 近藤 玲子, 川端 五十鈴
    1990 年 83 巻 5 号 p. 709-714
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Sudden sensorineural hearing loss has many causes and rarely occurs bilaterally. One patient with simultaneous bilateral sudden sensorineural hearing loss is presented.
    A 49-year-old female suffered from bilateral hearing loss after blowing of her nose. Experimental tympanotomy of the right ear revealed a perilymphatic fistula in the oval window. No recovery of hearing was attained after operation. A secretory line was seen on the left tympanic membrane as on the right, suggesting that both ears were in the same condition.
    If conservative treatment fails to restore hearing, surgery may be necessary to treat perilymphatic fistulas. Therefore we emphasize that perilymphatic fistulas should not be overlooked even though they are rarely bilateral.
  • 児玉 章, 河西 研一, 木村 元俊, 石塚 洋一, 山根 仁
    1990 年 83 巻 5 号 p. 715-722
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The relationship between age and three different pathological conditions of cholesteatoma (epitympanic, posteriorsuperior quadrant and mesotympanic) was analyzed in 88 patients. The middle ear pathology and pre- and post-operative hearing levels were examined.
    For posterior-superior quadrant and mesotympanic cholesteatomas, there were no age differences in the air conduction thresholds of speech frequencies or in middle ear pathology before tympanoplasty. For the epitympanic type, however, the air conduction thresholds were better and the middle ear pathology milder before age 40.
    The air conduction threshold after tympanoplasty was better in the epitympanic cholesteatoma group than in the other two groups and in younger patients in all three groups.
  • 守谷 啓司, 関谷 透, 木戸 利成, 緒方 正彦, 緒方 洋一
    1990 年 83 巻 5 号 p. 723-727
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The number of facial fractures has increased during the past several years.
    We have routinely treated facial fractures with open reduction and direct fixation. We obtained good results using a metal plate for patients with zygomatic fracture and a Kirshner wire for those with LeFort type fracture.
  • 深本 克彦, 杉田 麟也
    1990 年 83 巻 5 号 p. 729-734
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Case 1 was a 31-year-old male with extramedullary plasmacytoma (EMP) in the right maxillary sinus, who had no evidence of tumor 31 months after irradiation.
    Case 2 was a 16-year-old female with EMP on the left side of the nasal septum, which metastasized to the left superior cervical nodes 5 weeks after irradiation.
    PAP technique revealed that the tumor cells of Case 1 produced IgA-A chains and those of Case 2 produced IgG-K chains.
    Both patients underwent surgery and irradiation. For the metastasis of Case 2, the chemotherapy with Melphalan, Cyclophosphamide and Predonisone was administered before and after left radical neck operation, and there was definite regression of the tumor.
    These two patients were compared at several points and found clear hi.stological differences. In H. E. stained slides the tumor cells of Case 1 appeared to be welldifferentiated plasma cells, and those of Case 2 appeared to be less mature cells. This suggested that even in EMP the maturity of tumor cells affects the prognosis.
  • 柿木 章伸, 竹内 俊二, 岸本 誠司, 安岡 一夫, 細木 敬三, 玉井 嗣彦
    1990 年 83 巻 5 号 p. 735-739
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    A 55-year-old female with severe exophthalmos of 27mm was treated with the Walsh-Ogura method.
    CT scan and MRI showed that the severe exophthalmos was caused by enlargement of the extraocular muscles. The patient's left eye was treated with transantral orbital decompression.
    In addition, the infraorbital nerve and part of the inferior orbital rim were removed. Four months after surgery, the reduction in proptosis was 7mm. The patient's visual acuity was improved and she attained a satisfactory cosmetic result.
    After the operation, hypesthesia of the cheek was transient, but there were no other complications.
  • 西田 吉直, 内藤 泰, 本庄 巖
    1990 年 83 巻 5 号 p. 741-745
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Of 27 patients with unilateral paranasal sinus disease detected by CT scans, 15 had tumors and 12 had inflammatory disease or cysts. Most of those with malignant tumors had CT evidence of bone destruction. Maxillary sinus wall thickening was usually found in patients with inflammatory disease or cysts. However, two patients with malignant tumors showed only bone thickening. Therefore, pathological examination by biopsy or exploratory opening of the sinus should be performed when unilateral paranasal sinus disease is found.
  • 中村 雅一, 増田 成夫, 近藤 玲子, 川端 五十鈴
    1990 年 83 巻 5 号 p. 747-753
    発行日: 1990/05/01
    公開日: 2011/12/12
    ジャーナル フリー
    An 18-year-old boy visited our clinic complaining of painful swelling of the right cheek. CT scan and angiograms revealed a hypervascular lesion in the right maxillary sinus. The tumor was removed surgically under general anesthesia. Microscopic examination revealed histologic features compatible with angiofibroma. The reported cases of extranasopharyngeal angiofibroma are reviewed, and the pathogenesis, clinical features and treatment are discussed.
  • 福瀬 信也, 牧本 一男, 柴田 伊十児, 山本 祐三, 高橋 宏明, 芝山 雄老
    1990 年 83 巻 5 号 p. 755-760
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    An 81-year-old male complaining of nasal obstraction, epistaxis, and zygomatic swelling was admitted to Osaka Medical College Hospital. The histological diagnosis was metastatic maxillary tumor from a primary hepatocellular carcinoma. We employed intra-arterial infusion of ADM and BLM. These drugs were delivered through Tefron® catheters which were inserted into the right superficial temporal artery and hepatic artery. However, his general condition deteriorated gradually, and he died of hepatic failure. At autopsy, hepatocellular carcinoma was found to be of the massive type and Edmondson's type II and to coexist with Nagayo's type A cirrhosis. It had metastasized to the right maxillary sinus, lungs, and right adrenal gland. These metastases were considered to be hematogenous.
  • 羽熊 直行, 白根 誠, 平川 勝洋, 鈴木 衛, 夜陣 紘治, 原田 康夫
    1990 年 83 巻 5 号 p. 761-764
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    A maxillary cancer (T2N0M0) recurred twice, five years and 18 years after the initial therapy. The first therapy was continuous intra-arterial infusion of 5-FU (5700mg) and irradiation (50Gy). The second therapy was intravenous infusion of 5-FU (4500mg) and irradiation (46Gy). The third therapy was partial maxillectomy and LASER cauterization. In this particular case local inflammation due to remaining food and repeated irradiation might have been responsible for the recurrences.
  • 野村 淳, 田坂 康之, 野々村 光栄
    1990 年 83 巻 5 号 p. 765-769
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    A 24-year-old woman complained of pain of the radix nasi and disturbed visual acuity of 10 days duration. CT scan showed a tumor of the right ethmoid sinus extending into the right maxillary sinus. As much of the tumor was removed as possible through an extranasal approach and Caldwell-Luc operation. A diagnosis of rhabdomyosarcoma was established with special staining techniques.
    Postoperatively, this patient was treated with irradiation and chemotherapy (VCR, CTX, AMD, ADM). She is now asymptomatic 11 months after surgery, and radiographic or scintigraphic examinations reveal no local recurrence and distant metastasis.
  • 川井田 政弘, 福田 宏之, 川崎 順久, 甲能 直幸
    1990 年 83 巻 5 号 p. 771-775
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    A case of epiglottic cyst with pendulous appearance is reported. A 53-year-old man suffered from abnormal sensation of the throat and visited our clinic. At the initial examination, a pale yellow cystic lesion was observed on the left side of the lingual surface of the epiglottis. At the next examination, a cystic lesion was observed on the right aryepiglottic fold, and the location of the cystic lesion was different on all subsequent visits. Laryngomicrosurgery through a direct laryngoscope was performed to remove the cystic lesion. The excised lesion had a long stalk and a pendulous appearance. The histopathological diagnosis was epidermoid cyst. The histopathological findings of the stalk were similar to those seen in the stalk portion of pendulous tonsils, suggesting a common etiology of this lesion and pendulous tonsil.
  • 渋沢 三伸, 羽成 敬一
    1990 年 83 巻 5 号 p. 777-784
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    As in the case of unilateral vocal cord paralysis, the clinical symptoms of bilateral vocal cord paralysis differ according to the position in which vocal cords are fixed and the shape of the vocal cords themselves.
    In most cases of unilateral vocal cord paralysis, disphonia is the main problem. On the other hand, problems associated with respiration and swallowing are equally important to those of phonation in cases of bilateral vocal cord paralysis.
    Patients with bilateral vocal cord paralysis are classified into two groups. One group consists of patients whose vocal cords are both fixed in the midline position; the other group of those whose vocal cords are in other positions. Both groups are subdivided into two groups according to whether their vocal cords show atrophy (bowing) or not.
    In patients with bilateral vocal cord paralysis, the clinical symptoms are qualitatively different depending on the fixed vocal cords' position. Therefore, it is important for both patients and doctors to define the purpose of treatment; in other words, to define which is to be cured, dyspnea or dysphonia.
  • 増満 洋一, 関谷 透, 野口 高昭
    1990 年 83 巻 5 号 p. 785-788
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Peplomycin-induced pulmonary fibrosis disturbs unexpectedly and unfortunately the schedule of treatment with anti-cancer drugs. Recent pharmacological experiments in animals disclosed that ticlopidine may be useful in suppressing peplomycin-induced pulmonary fibrosis. We investigated clinically the suppression by ticlopidine of peplomycin-induced pulmonary fibrosis.
    Ticlopidine was administered orally to ten patients with head and neck cancer who were being treated with peplomycin, and its suppression of peplomycin-induced pulmonary fibrosis was evaluated by noting the changes in pulmonary fibrosis markers: angiotensin I converting enzyme (ACE), phospholipid (PL), malondialdehyde (MDA) and type III procollagen peptide (Type III p. p.) . Serum analysis showed no change in ACE, but PL increased significantly, indicating that ticlopidine can suppress peplomycininduced pulmonary fibrosis.
  • 竹内 俊二, 竹田 泰三, 齋藤 春雄
    1990 年 83 巻 5 号 p. 789-792
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The pressure difference between the perilymph and the endolymph was studied in guinea pigs, with the use of two sets of a servo-nulling system. An increase in the penlymphatic pressure induced by the infusion of artificial cerebrospinal fluid into the subarachnoid space resulted in an increase in the endolymphatic pressure, but no pressure difference between the endolymph and the perilymph was evident, regardless of the patency of the vestibular aqueduct. The authors conclude that the endolymphatic pressure is dependent on the perilymphatic pressure and there is no pressure difference between them.
  • 土師 知行
    1990 年 83 巻 5 号 p. 793-808
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Simple and objective methods were developed to evaluate the mechanical properties of the vocal fold in relation to mobility of the vocal fold mucosa and stiffness of the vocal fold. Mobility of the vocal fold mucosa was measured with a fine suction tube, and stiffness of the vocal fold was evaluated by analyzing stress-strain curves in human and canine excised larynges under various conditions.
    1) Mobility of the vocal fold mucosa was greatest in the middle of the membranous portion and less around the anterior commissure and the vocal process. Stiffness of the membranous portion of the vocal fold was least at the middle and greater around the anterior commissure and the vocal process. Mobility of the false vocal fold mucosa was much greater, and stiffness of the false vocal fold was much less, than those of the true vocal fold.
    2) As the vocal fold tension increased, mobility of the vocal fold mucosa decreased and stiffness of the vocal fold increased as the vocal pitch rose. Marked differences of the mechanical properties were observed between the “body” and the “cover” of the vocal fold, especially when tension was applied to the vocal fold.
    3) When the vocalis muscle contracted, the vocal fold tended to be less stiff and more viscous.
    4) When the vocal fold mucosa became dry, stiffness of the vocal fold became greater.
    5) Submucosal injection of saline solution reduced mobility of the vocal fold mucosa and increased stiffness and viscosity of the vocal fold.
  • ―第2報:癌細胞検出の基礎的研究―
    山崎 典子, 堀 芳朗, 榊 徳子, 和田 安弘, 岡 茂, 山下 敏夫, 熊澤 忠躬, 河本 圭司
    1990 年 83 巻 5 号 p. 809-815
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Attempts have recently been made in many fields to apply flow cytometry measurement of DNA in tumor cells in the assessment of malignancy. In cancers of the head and neck, however, analysis of DNA histograms is complicated by the presence of various amounts of non-epithelial cells, including inflammatory cells. We theorized that the use of a monoclonal antibody for cytokeratin, a protein found i n the intermediate filament of epithelial cells, may make possible, the isolation of epithelial cells from tumor tissue, thereby enabling the determination of the DNA content of tumor cells. In the present study, we examined propidium iodide-fluorescein isothiocyanate-labelled-cytokeratin double staining by monoclonal antibody in KB cells. We succeeded in isolating KB cells from a mixture of KB cells and lymphocytes.
  • ―十味敗毒湯内服の有用性―
    市村 恵一, 池田 利昭, 田中 利善, 沖田 渉
    1990 年 83 巻 5 号 p. 817-823
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    Placement of a ventilation tube through the eardrum is regarded as an effective treatment for recalcitrant cases of otitis media with effusion. A few patients may develop otorrhea either in the immediate postoperative period or later. The discharge is from a wound infection or the result of the underlying disease process. Conservative treatment, including cleaning the ear under the microscope, curetting and cauterizing granulations, and topical drops, along with oral antibiotics is usually selected for the condition. If this type of treatment fails, most of the ENT doctors remove the tube, which is quite effective. However, such patients usually have stubbornly resistant effusion and may require another tube insertion. We use Jumi-Haidoku-to granules (Kampo type of herb medicine) for discharges that resist therapy. Seven patients (8 ears) who suffered from postintubation otorrhea were treated successfully, without removal of the tubes, using oral Jumi-Haidoku-to with or without oral antibiotics. The postoperative use of this medicine in a 10-year-old boy with cholesterol granuloma is also described.
  • 石川 保之, 藤村 英一
    1990 年 83 巻 5 号 p. 825-829
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
    The therapeutic effect of S-carboxymethyl cysteine (Mucodyne®) was examined in 20 children with chronic sinusitis. About 30mg/kg/day of Mucodyne® was administered and the efficacy was evaluated after 8 weeks of treatment.
    1) The effectiveness on x-ray examination was 80%.
    2) Nasal airway resistance and saccharin time improved significantly after 8 weeks.
    3) The concentration of S-IgA in nasal secretions was decreased significantly after 8 weeks.
    4) No side effect was noted.
  • 野村 恭也
    1990 年 83 巻 5 号 p. 830-831
    発行日: 1990/05/01
    公開日: 2011/11/04
    ジャーナル フリー
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