抄録
Primary malignant melanoma of the larynx is very rare. We treated a 79-year-old man with double laryngeal cancer including malignant melanoma and squamous cell carcinoma.
The patient consulted our hospital with compliant of hoarseness and a left neck mass noticed 2 weeks previously. A blue-black tumor was found on the left vocal cord. Preoperative fiberscopic biopsy of the tumor revealed squamous cell carcinoma. Total laryngectomy and left radical neck dissection were performed.
Postoperative histological analysis was performed with H-E staining, HMB-45, and S-100 immunological staining. Malignant melanoma had arisen in the subepithelium of the left vocal cord, and formed nets with spindle cells and melanin. In another portion of the left vocal cord, squamous cell carcinoma had arisen in the epithelium, and formed sheets without melanin. The final diagnosis was double laryngeal cancer including malignant melanoma and squamous cell carcinoma.
The origin of these two tumors was discussed. The combination of these two cancers is very rare.
