The order of four homeotic-mutant genes, Nc, E^Cw, E^Kp and E^Mu, on the 6th-linkage group of Bombyx mori

抄録

The Nc-mutant gene and E pseudoalleles of Bombyx mori correspond to the Antennapedia and bithorax complexes of Drosophila melanogaster, respectively. The arrangement of the Nc-mutant gene and three mutant genes, E^Cw, E^Kp and E^Mu, belonging to the E-pseudoallelic genes located on the sixth-linkage group, was investigated by genetic analysis. It indicated that the arrangement of the four mutant genes is in the order of E^Mu-E^Kp-E^Cw-Nc from the proximal side of the sixth-linkage group, and genetic distances between adjacent loci were calculated to be 0.72 centimorgans (cM) between E^Mu and E^Kp, 0.57cM between E^Kp and E^Cw, and 2.20cM between E^Cw and Nc. The order of these genes on the chromosome corresponds to the order of segments in which each mutant gene primarily expresses the mutant characteristics along the anteroposterior axis, in a similar way to those of Drosophila melanogaster and Tribolium astaneum.