Abstract
Ulcerative colitis (UC) was regarded as an autoimmune disease after the concept of autoimmunity was proposed, and the bacterial cause theory was not regarded as very important. However, when intestinal bacteria again became suspected as a cause of UC or an inflammation exacerbation factor more studies were performed, and the mechanism of UC onset was identified as bacterial. In this review, I report a Fusobacterium varium cause theory, and the antibiotic combination ATM therapy for UC that we propose with the general remarks about the enterobacterial role in the ulcerative colitis. I also will review the relationship between Fusobacterium and colorectal carcinoma.
