原子間力顕微鏡による有機結晶表面の水和構造観察とその多形間および結晶面間での比較

抄録

  Understanding of crystallization and crystal growth of organic crystals is essential for promoting the development of techniques for controlling crystallization and morphology. We are investigating the crystal growth mechanism of organic crystals from a viewpoint of hydration structure at an organic crystal surface-solution interface using three-dimensional (3D) force distribution measurement by atomic force microscopy (AFM). In this article, it is revealed that hydration structures of acetaminophen crystals are different between polymorphs and that those of α-glycine crystals are different between crystal planes. Then, the influence of the different hydration structures on crystal growth of polymorph and morphology is discussed.