The gustatory and feeding responses to amino acids were investigated in the silkworm, Bombyx mori L. Gustatory responses to L-isoleucine and L-leucine were observed in the sensory hair, Ss-I. The sensory hair, Ss-II, responded to L-arginine-HCl, L-histidine-HCl-H2O, L-leucine, L-lysine and L-tryptophan. The responses of the receptor cells to amino acids, isoleucine and leucine, disagreed with that of any type of the receptor cells in Ss-I. On the other hand, the responses of the receptor cells in Ss-II to amino acids, L-arginine-HCL, L-histidine-HCl-H2O, L-leucine, L-lysine and L-tryptophan, agreed with that of R-cells (the receptor to repellents, such as “bitter substances”). The feeding responses decreased with increasing concentrations of each amino acid, L-arginine-HCl, L-histidine-HCl-H2O, L-lysine or L-tryptophan. These results showed that the feeding responses to amino acids were closely related to the responses of the R-cells.