計量生物学
Online ISSN : 2185-6494
Print ISSN : 0918-4430
ISSN-L : 0918-4430
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移設推定値を用いた後ろ向きコホート研究によるメタボリック症候群のリスク評価
石田 紀子市丸 晋一郎飛田 あゆみ早田 みどり中村 剛赤星 正純
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2009 年 30 巻 2 号 p. 93-104

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The validity of the diagnostic criteria for Metabolic Syndrome (MS) has been questioned since the syndrome was introduced. To verify their validity, the best strategy would be a cohort study. However, waist circumference (WC), which is necessary for the diagnosis of MS, was introduced to health examinations only recently. If a current regression model of WC could be transported to a previous sample, a cohort study using estimates of WC would be possible. We propose a sufficient condition for the transportability from a mathematical point of view. Using data from the Radiation Effect Research Foundation, we examined whether the proposed condition may be statistically confirmed in a real dataset. The regression model for weight, which is strongly associated with WC, was used to verify the validity of the condition. The relative risk of death from MS-related causes was obtained. The results indicated that the risk was lower with a greater WC.

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© 2009 日本計量生物学会
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