育児用調製乳および乳製品中のヒ素を対象とした標準試験法（AOAC Official Method 2015.01）の多様性改良

抄録

This study aims to improve the versatility of AOAC Official Method 2015.01 (Method 2015.01) for the determination of arsenic in infant formula and milk products in international trade. The sample preparation was changed from a wet ashing method using a microwave digester to a dry ashing one with an electric furnace, which will simplify the process and allow the processing of several samples. Magnesium nitrate solution was added before dry ashing to prevent arsenic volatilization. Importantly, helium was used as a replacement for oxygen as the reaction cell gas during sample measurement with inductively coupled plasma mass spectrometry, for making the process highly versatile. The modified method exhibited excellent linearity over the concentration range of the standard solutions, and all the conditions (lower limit of quantification, repeatability, and recovery factor) of the Standard Method Performance Requirement of AOAC International were met. When the sample used in the proficiency test for the trace element, provided by KANSO CO., LTD. (PTP-1801WR), was measured, the result was close to the value allowed by KANSO CO., LTD. By modifying the sample preparation and the reaction cell gas, we enhanced the versatility of Method 2015.01 for the analysis of arsenic in infant formula and dairy products.