抄録
We validated an alternative testing method for the determination of dibutyltin (DBT) compounds in food utensils, containers,
and packaging products made from polyvinyl chloride using gas chromatograph-mass spectrometry with nitrogen (N2) as a carrier
gas. The retention times, mass spectra, ion intensities, and signal-to-noise-ratios (S/N) of a DBT derivative were compared using
both helium and N2 as the carrier gas. The retention times were almost equal under the same flow-rate condition, as were the mass
spectra. In contrast, the ion intensity with the N2 carrier gas decreased to around 3/4, and the S/N decreased significantly to 1/10. This
might be due to the increase in background noise level. We validated the performance in terms of a limit testing method that assess
its suitability by comparing the peak area values of the DBT derivative in the test solution and a standard solution at a concentration
corresponding with the acceptance criteria and a quantitative testing method with N2 carrier. All parameters corresponding to the
trueness, repeatability, and reproducibility as intermediate precision, satisfied the target values in both cases, indicating that both
approaches demonstrate good performance as a testing method.
