Abstract
Objective In the current study, we aimed to evaluate the safety of excessive intake of a dietary supplement containing Proteoglycan complex 80, derived from salmon nasal cartilage.
Methods This randomized, double-blind, placebo-controlled, parallel-group study enrolled 30 participants (39.5±9.7 years [mean±standard deviation]) who ingested a dietary supplement containing 200 mg of Proteoglycan complex 80 or placebo for four weeks. General blood and urine biomarkers for health and medical conditions were analyzed at 0, 2, 4, and 6 weeks.
Results There were no clinically relevant changes related to the test supplement. Furthermore, there were no side effects related to the intake of Proteoglycan complex 80.
Conclusion Our findings demonstrated the safety of excessive intake of the dietary supplement containing Proteoglycan complex 80 derived from salmon nasal cartilage.
