日本食品化学学会誌
Online ISSN : 2189-6445
Print ISSN : 1341-2094
ISSN-L : 1341-2094
サケ鼻軟骨由来プロテオグリカン複合体80 の過剰摂取時における安全性の検討
―プラセボ対照ランダム化二重盲検並行群間比較試験―
和田 竜哉小鮒 保雄戸井田 敏彦
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ジャーナル フリー

2023 年 30 巻 3 号 p. 165-177

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抄録
Objective In the current study, we aimed to evaluate the safety of excessive intake of a dietary supplement containing Proteoglycan complex 80, derived from salmon nasal cartilage.
Methods This randomized, double-blind, placebo-controlled, parallel-group study enrolled 30 participants (39.5±9.7 years [mean±standard deviation]) who ingested a dietary supplement containing 200 mg of Proteoglycan complex 80 or placebo for four weeks. General blood and urine biomarkers for health and medical conditions were analyzed at 0, 2, 4, and 6 weeks.
Results There were no clinically relevant changes related to the test supplement. Furthermore, there were no side effects related to the intake of Proteoglycan complex 80.
Conclusion Our findings demonstrated the safety of excessive intake of the dietary supplement containing Proteoglycan complex 80 derived from salmon nasal cartilage.
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