Abstract
A 75-year-old woman was referred to our hospital with vague epigastric pain. At age 53, she was suspected to have a benign tumor of the pancreas head, and pancreaticoduodenectomy was performed. At that time, a pancreatic tumor producing somatostatin was diagnosed. At age 55, a partial hepatectomy was performed, and she was given a diagnosis of liver metastasis of the tumor producing somatostatin. Acute exacerbation of chronic pancreatitis was finally diagnosed, and abdominopelvic computed tomography revealed a 28×20 mm low density mass and a hypervascular lesion in the left lateral segment of the liver (S3). Based on a preoperative diagnosis of liver metastasis of an endocrine tumor, we performed a segmentectomy in the patient at her most recent referral. A histological examination of the specimen demonstrated another liver metastasis from the tumor producing somatostatin. Tumors producing somatostatin are extremely rare endocrine tumors mainly found in the pancreas or duodenum. We report a case of a long-term survivor of a pancreatic tumor producing somatostatin with liver metastasis treated by partial hepatectomy two and 22 years after initial surgery.
