Abstract
A 69-year-old man with pancreatic head cancer who had received preoperative gemcitabine-based chemoradiation therapy and subsequent pancreaticoduodenectomy, combined with postoperative liver perfusion chemotherapy, was found to have a tumor in the upper lobe of right lung 31 months after the initial pancreatic resection. Because of the absence of recurrence of pancreatic cancer in other sites than the right lung, the patient underwent right upper lobectomy. The diagnosis of lung metastasis originating from pancreatic cancer was confirmed based on histological as well as immunohistopathological assessments. The patient has been alive without tumor relapse for more than 5 years after the second operation for the lung metastasis. This case indicates that an aggressive surgical approach for lung metastasis originating from pancreatic cancer possibly results in a favorable outcome in selected cases.