1992 年 33 巻 2 号 p. 213-216
Inhibitive effects of estrogen and progesterone on the yeast form growth of Paracoccidioides brasiliensis were examined using brain heart infusion broth with different doses of these hormones. The yeast form growth of P. brasiliensis was inhibited by estrogen within the range of physiological concentrations; this inhibition was dose dependent. Progesterone weakly inhibited the growth. The phenomenon that estrogen inhibited the yeast form growth of the fungus might be one of the important reasons for the sexual difference in susceptibility in paracoccidioidomycosis.