Abstract
This is a rare report of multiple oral carcinoma originating in an erythroplakia. The patient is a 76-year-old woman with no drinking or smoking habit. An expansile erythroplakia, ranging from the right palate to the right buccal mucosa and from the lower lip to the left buccal mucosa, was observed in her oral cavity. The biopsy specimen was diagnosed as mild epithelial dysplasia. One and a half years after the first visit, a squamous cell carcinoma emerged on the right buccal mucosa, and the lesion was surgically excised. At the point of seven and a half years from the first visit, a massive squamous cell carcinoma appeared on the median portion of the lower gingiva. Radiotherapy and chemotherapy failed to control the lesion, and the patient died of pulmonary metastases.
