Desmoplastic fibroma is a benign mesenchymal tumor originating from bone. It grows slowly and is characterized by strong local infiltration and recurrence. We report a case of desmoplastic fibroma arising in the anterior tooth region of mandible that was treated by conservative surgery. The patient was a 20-year old woman. She felt oppressive pain in the anterior tooth region of the mandible in July 2013. Her dentist found a radiolucent lesion in the affected region and referred her to our clinic in August. At presentation a clinical examination revealed bone expansion and oppressive pain from the left central incisor to the first premolars of the mandible. A panoramic x-ray film showed a well-defined unilocular radiolucent region in the affected front mandibular tooth. In September, a biopsy was performed with the patient under local anesthesia. Histopathologically, the mass was diagnosed as a desmoplastic fibroma. In October, the patient expressed her strong desire to undergo conservative surgery, even though it carried an increased risk of recurrence; thus, enucleation and curettage were performed with the patient under general anesthesia. The tumor was easily separated from the surrounding bone. No recurrence has occurred as of 3 years 2 months after the operation.
