Malignant lymphoma is a generic name given to the neoplasms arising from the lymph node and lymphoid tissues.
We report here the process of the treatment and the analysis of the histological features of three cases which were classified as stage I of non-Hodgkin's lymphoma according to the stage classification settled at the Ann Arbor conference. The tumors of all three were confined to unilateral submandibular lymph node region. The radiation therapy after surgical procedure, extirpation of the tumor, was done in such a way that the target might absorb a total dosage of 4, 000 rads in 4 weeks. Prophylactic irradiation with 4, 000 rads was also delivered to the entirety of Waldeyer's ring, the neck and surpraclavicular fossae.
Radiotherapy has been the treatment of choice for the large majority of patients with non-Hodgkin's lymphoma localized nodally or extranodally in stage I to II.
The analysis of the histological feature: The three cases were all diffuse lymphomas. Two cases were classified as the histiocytic type, and the other was classified as the mixed lymphocytic and histiocytic type by Rappaport's classification. According to LSG (Lymphoma-Study-Group) classification, the three cases were classified as the pleomorphic type, the mixed type and the large cell type, respectively. All of them have been progressing favorable with a tendency of remission but no evidence of relapses for the past 6 years, 4.5 years and 2 years, respectively, since surgical and radiological therapies.
