下顎骨に発生した単骨性線維性骨異形成症の1例

抄録

Monostotic fibrous dysplasia is a benign disease, which may appear in a single bone and is mainly consisted of fibrous changes in the bone marrow, however, the presence or absence of tumorigenesis in this disease is now more passively discussed than passed days because of problems existing in the differentiation from related bone diseases or in the method of operation. In addition, this disease is also interested because of its less occurrence in the jaw and oral regions. Recently, we experienced this disease appearing in the left mandibula and examined in detail. The result will be described below with some considerations.
A 57 year-old woman came to our hospital with a main complaint of swelling in the left mandibular molar. Her face was slightly asymmetric. X-ray films showed an opaque, well defined and thumb-tip sized mass in the left mandibular osseous body. These findings first suggested an ossifying fibroma but the diagnosis of fibrous dysplasia was finally made based on the histopathological findings.
The infrared spectrometric analysis revealed the chemical components to be 31% Ca₃ (PO₄) ₂ and 69% MgNH₄ PO₄·6H₂O. In addition, the crystal structure was analysed by X-ray diffraction, resulted in the identification of hydroxyapatite with less crystalline property.