HLA Typing of Carcinoma Linguae in two Brothers.
We examined prosthetic appliance, smoking, drinking, habits, and HLA antigen in 4 brothers including 2 patients with carcinoma linguae.
In all these brothers, metal crown or artificial tooth was applied.
Two brothers suffering from carcinoma linguae smoke about 20 cigarettes a day. while other two healthy brothers smoke about 40 cigarettes a day.
All of them have a history of little drinking but no adverse habits in the food life to be mentioned specially.
HLA typing of peripheral lymphocytes was performed by microlymphocytotoxicity method. In consequence, no increasing or decreasing trend of HLA antigen was demonstrated between the two groups.