Ostopetrosis is characterized by a prominent radiologic feature of generalized skeletal sclerosis. The disease is divided into a severe malignant type which appears in infants or children and a benign type which usually appears in adults.
Osteomyelitis is a serious complication of osteopetrosis, occurring most frequently in the mandible. We present here a 35-year-old male patient with osteopetrosis associated with mandibular osteomyelitis which was caused by the extraction of an impacted wisdom tooth. The osteomyelitis was successfully treated by extensive surgical debridements and sequestrectomies.