自家海綿骨骨髄小片充填移植による下顎枝再建に関する実験的研究

抄録

To determine the value of the reconstructive method by the autogenous cancellous bone and marrow chip grafts to mandibular defect sites which involved upper areas from Foramen mandibulae, i.e., Ramus mandibulae, Processus condylaris and coronoideus, a study of 56 and the macroscopic, radiographic, histopathologic, and the fluorescent findings of adult dogs was done with the conclusions as follows:
1. Although minor osteogenesis was perceived to locally exist at the end of the host bone, no bone formation was observed in nongrafting groups both under the periosteum or nonperiosteum.
2. Normal remodelling of Processus condylaris, Caput mandibulae, Processus coronoideus and Ramus mandibulae was viewed for 4 months in grafting groups with periosteum. Caput histologic construction was nearly normal. Hardness of the new bone was sufficient and smooth bony adhesion to the host bone was observed.
3. Only the bone grafted proximal to the host bone was fixed and that grafted far from it was absorbed, and functional morphologic recovery of Caput mandibular was found to be negative in grafting groups without periosteum.
4. Autogenous cancellous bone and marrow chip grafts were especially efficient, when periosteum exists, and this suggests multiplicated effect between periosteum and the grafted bone. Periosteum effectively acted on inhibiting the surrounding tissue from the invading grafted bone.