嚢胞を形成した顎下腺多形性腺腫の1例

抄録

Pleomorphic adenoma frequently occurs in the parotid gland and palatine glands but is relatively rare in the submandibular gland.
Recently, we experienced a case of pleomorphic adenoma of the right submandibular gland with a large cyst in the tumor center.
The 55-year-old woman patient, was aware of a painless swelling of the right submandibular region for 5-years. She had not recieved any treatment but recently visited our department because of tumor expansion.
This tumor was removed with submandibular gland.
Microscopically, the parencyma of the tumor consisted of multipicated epitherial cells, partly like a tubular gland and metaplasia of squamous epithelium. The stroma had myxomatous structure and the cyst wall lacked epithelium. Histological diagnosis was pleomorphic adenoma.
This lesion is about 60% of all salivary gland tumors but rarely occurs is in the submandibular gland. This tumor sometimes forms a cyst in a long progress, although there is no consensus of views about its forming process.
Surgical excision that includes the submandibular gland is the best treatment. The patient must be carefully followed because of the tendency of recurrence.