Amyloidosis is a lesion which amyloid substance, fibrous protein, is deposited in all organs and tissues of the body.In the oral region, tongues are most affected. Lips, cheeks, palates and submandibular salivary glands may also be affected, but few cases were reported so far.
Clinical classification of amyloidosis is generally as follows;(1) primary amyloidosis, (2) amyloidosis with multiple myeloma, (3) secondary amyloidosis, (4) hereditary amyloidosis, (5) organ limited amyloidosis.
Recently, we have experienced a case of amyloidosis, which had occured in both cheeks of a 45-year old man.The patient complained of a tumor formations of both cheeks.These tumors were excised intraorally and amyloid fibrils were detected in them by light and electron microscopy.Furthermore, by several systemic examinations this case was diagnosed as organ limited amyloidosis.
