日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
Gardner症候群の1症例
佐藤 公治阿部 麻子奥井 美枝辻川 孝昭日比 五郎岡 達
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1987 年 33 巻 1 号 p. 179-183

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Gardner's syndrome is a hereditary disease characterized by the triad of soft tissue tumor, hard tumor (osteoma) and multiple intestinal polyposis and is also accompanied by a variety of dental abnormalities.It has been reported that early diagnosis is essential as intestinal polyposis in particular, has a high malignant pontential.In this paper, a case study is reported on a patient with complete Gardner's syndrome discovered on presentation for examination at our Department of Oral Surgery and a medical documentation is also included. The patient was a thirty-five years old male who presented for initial diagnosis with a hard tumor in both mandibular angles and a bean-sized atheroma-like tumor in theepithelium of the right oral angle. X-ray findings revealed osteoma-like radiopaque in the maxilla and mandibular as well as several impacted teeth.In addition, the patient had a history of tumor resection in the dorsal, right orbital epithelium. Based on the above findings, Gardner's syndrome was suspected and gastrointestinal surgery was subsequently conducted.Surgical findings revealed multiple polyps occurring in the region from the stomach through the small intestine to the large intestine and complete Gardner's syndrome was diagnosed.The largest polyp found in resected intestine was 5 cm in diameter, and although it was found to be pathohistologically adenoma, malignant findings were not observed.

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