Abstract
A/J mice are infected with MMITV (mouse-mammary-tumor-virus) and the transcription of this virus is significantly stimulated by glucocorticoid. This study was aimed to find out the role of MMTV in glucocorticoid-induced cleft palate.
Findings were as follows:
C 3 H/HeN MTV-, BALB/c and C 57 BL/10 mice, which were inoculated with MMTV from AJ mice, were found to become susceptible to glucocorticoid-induced cleft palate.
Therefore, MMTV was confirmed to be able to influence susceptibility to glucocorticoidinduced cleft palate in mice.
