Adenomatoid odontogenic tumor

Immunohistochemical detection of intermediate filament proteins

Abstract

Adenomatoid odontogenic tumor (16-year-old female) in the anterior mandibule was described, and immunohistochemicall detectable intermediate sized filament proteins were also examined in tumor tissue.
Histologically, the tumor cells could be divided into two types; the type A cells showed spindle and columnar in shape and formed solid, ductal, tubular or whorled structures, and the type B cells showed small and compact cells located at the periphery of the A cell-containing forus.
Immunohistochemically, the A tumor cells expressed slight or no staining to keratins, and the B tumor cells were characterized by co-expression with keratins and vimentin.