実験的咬合異常によるラット顎関節関節円板における血管構築の変化

抄録

Changes in vascularization on the articular disk of temporomandibular joint (TMJ) under the condition of unilateral mastication in rats were observed.
Forty 8-week-old male Wistar rats were used. In 20 rats, the right upper 3 molar teeth were extracted and the right upper incisal was amputated at the gingival margin. The other 20 rats were served as controls. After 4 months, the rats were killed and the articular disks of TMJ were dissected carefully. After fixation in 10% formaldehyde, the specimens were embedded in paraffin, and 20μ thick serial sections were cut along the longitudinal axis of the articular disk. After Peroxidase staining according to the Graham-Karnovsky method and staining with Methyl green, the specimen weres observed microscopically. The following findings were obtained;
1. In 9 rats of the experimental group, vascularization was found.
2. Vascularization was found on the articular disks of TMJ of both the operated and the unoperated side.