1990 年 36 巻 12 号 p. 2830-2834
A case of teeth extraction in a patient with von Willebrand's disease was reported. The patient, a 19-year-old female, complaning of toothache of the mandibular right third molar visited our clinic. Twenty units of commercial heated factor VIII concentrates (Confact F®) per kg body weight was infused preoperatively. Then teeth extraction of the mandibular right third molar, left second premolar, and second molar was performed. No secondary bleeding was noticed after operation. Confact F®, including intermediate multimers of von Willebrand factor, was effective to correct abnormal hemostasis in the patient with von Willebrand's disease.