1993 年 39 巻 11 号 p. 1258-1260
A case of drug-induced esophageal ulcer caused by cefotiam hexetil hydrochloride is reported. The patient was a 65-year-old man. He took cefotiam hexetil hydrochloride tablets after extraction of the third lower molar. Dysphagia developed on the day following drug intake. Esophagoscopy revealed superficial ulcers in the Middle part of the esophagus. He was treated with an H2-blocker and antiacids and his symptoms disappeared 1 week after onset. The acute presence of these ulcers was attributed to the large size of the tablets and swallowing difficulty occurring after tooth extraction.