An odontogenic myxoma is reported. A 21-year-old man complained of painless swelling at the left lower molar region. Radiographs of the lesion showed a intra-bony mutilobular radiolucency. Examination of a biopsy specimen suggested an odontogenic myxoma. The lesion was managed by mandibulectomy under general anesthesia, immediately followed by iliac autograft and sural nerve transplantation. Histological examination revealed loosely arranged, spindle-shaped and stellate cells with fine collagen fibers. Odontogenic epithelial cell nests were found among the myxomatous cells. From these findings, the lesion was diagnosed as an odontogenic myxoma. The patient was observed a year later and no evidence of recurrence was detected.
